Intraspinal AAV Injections Immediately Rostral to a Thoracic Spinal Cord Injury Site Efficiently Transduces Neurons in Spinal Cord and Brain

• Main Authors: Michelle C Klaw (Author), Chen Xu (Author), Veronica J Tom (Author)
• Formato: Livro
• Publicado em: Elsevier, 2013-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In the vast majority of studies utilizing adeno-associated virus (AAV) in central nervous system applications, including those published with spinal cord injury (SCI) models, AAV has been administered at the level of the cell body of neurons targeted for genetic modification, resulting in transducti...