Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC

• Main Authors: Xinchen Liu (Author), Lin Meng (Author), Xing Li (Author), Daowei Li (Author), Qilin Liu (Author), Yumeng Chen (Author), Xiangwei Li (Author), Wenhuan Bu (Author), Hongchen Sun (Author)
• Format: Book
• Published: Nature Publishing Group, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Epithelial-mesenchymal transition (EMT) is involved in both physiological and pathological processes. EMT plays an essential role in the invasion, migration and metastasis of tumours. Autophagy has been shown to regulate EMT in a variety of cancers but not in head and neck squamous cell car...