Clemastine Ameliorates Perioperative Neurocognitive Disorder in Aged Mice Caused by Anesthesia and Surgery

• Main Authors: Wensi Wu (Author), Xiaojun Zhang (Author), Jiaxin Zhou (Author), Hongmei Yang (Author), Junjun Chen (Author), Le Zhao (Author), Junying Zhong (Author), Wei-jye Lin (Author), Zhi Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Perioperative neurocognitive disorder (PND) leads to progressive deterioration of cognitive function, especially in aged patients. Demyelination is closely associated with cognitive dysfunction. However, the relationship between PND and demyelination remains unclear. Here we showed that demyelinatio...