Apatinib-loaded CalliSpheres Beads for embolization in a rabbit VX2 liver tumor: characterization in vitro, pharmacokinetics and tumor response in vivo

Apatinib mesylate is an oral antiangiogenic agent that can inhibit activation of vascular endothelial growth factor receptor-2 tyrosine kinase. However, its therapeutic use in liver cancer is restricted due to severe systemic toxicity. Our work aimed to construct apatinib-loaded CalliSpheres Beads (...

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Bibliographic Details
Main Authors: Qin Shi (Author), Yongning Lu (Author), Songjiang Huang (Author), Chen Zhou (Author), Chongtu Yang (Author), Jiacheng Liu (Author), Jinqiang Ma (Author), Bin Xiong (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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