Untargeted metabonomics and TLR4/ NF-κB signaling pathway analysis reveals potential mechanism of action of Dendrobium huoshanense polysaccharide in nonalcoholic fatty liver disease

• Main Authors: Guang-hui Deng (Author), Chen-chen Zhao (Author), Xiao Cai (Author), Xiao-qian Zhang (Author), Meng-zhen Ma (Author), Jia-hui Lv (Author), Wen-li Jiang (Author), Dai-yin Peng (Author), Yan-yan Wang (Author), Li-hua Xing (Author), Nian-jun Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD) is marked by hepatic steatosis accompanied by an inflammatory response. At present, there are no approved therapeutic agents for NAFLD. Dendrobium Huoshanense polysaccharide (DHP), an active ingredient extracted from the stems of Dendrobium Huoshanense, and e...