β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis

• मुख्य लेखकों: Di Zhang (लेखक), Fei Ge (लेखक), Jing Ji (लेखक), Yu-Jing Li (लेखक), Fu-Rong Zhang (लेखक), Shu-Yan Wang (लेखक), Shu-Jing Zhang (लेखक), Dong-Mei Zhang (लेखक), Meng Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Inflammation-related NLRP3/Caspase-1/GSDMD-mediated pyroptosis is involved in the progression of ulcerative colitis (UC). β-sitosterol (SIT) was reported to have anti-inflammatory effects on experimental colitis, while the regulation of SIT on pyroptosis is unclear. Therefore, the presen...