Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era

• Asıl Yazarlar: Chansey J. Veinotte (Yazar), Graham Dellaire (Yazar), Jason N. Berman (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2014-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The current preclinical pipeline for drug discovery can be cumbersome and costly, which limits the number of compounds that can effectively be transitioned to use as therapies. Chemical screens in zebrafish have uncovered new uses for existing drugs and identified promising new compounds from large...