Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model

• Main Authors: Sergio Li Calzi (Author), Todd Cook (Author), Domenico G. Della Rocca (Author), Juan Zhang (Author), Vinayak Shenoy (Author), Yuanqing Yan (Author), Andrew Espejo (Author), Anandharajan Rathinasabapathy (Author), Max H. Jacobsen (Author), Tatiana Salazar (Author), George E. Sandusky (Author), Lynn C. Shaw (Author), Keith March (Author), Mohan K. Raizada (Author), Carl J. Pepine (Author), Michael J. Katovich (Author), Maria B. Grant (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We compared the functional outcome of Isl-1+ cardiac progenitors, CD90+ bone marrow-derived progenitor cells, and the combination of the two in a rat myocardial infarction (MI) model. Isl-1+ cells were isolated from embryonic day 12.5 (E12.5) rat hearts and expanded in vitro. Thy-1+/CD90+ cells were...