Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment

Low-density lipoprotein (LDL) receptor (LDLR) mutations are the primary cause of familial hypercholesterolemia (FH). Class II LDLR mutations result in a misfolded LDLR retained in the endoplasmic reticulum (ER). We have developed a model of FH class II and CRISPR-corrected induced pluripotent stem c...

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Main Authors: Linda Omer (Author), Lubna Hindi (Author), Giuseppe Militello (Author), Katlin B. Stivers (Author), Kenneth C. Tien (Author), Nolan L. Boyd (Author)
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出版: The Company of Biologists, 2020-04-01T00:00:00Z.
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3rd Floor Main Library

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索引号: A1234.567
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