Aging‐related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle

• Main Authors: Patricia Sosa (Author), Elena Alcalde‐Estévez (Author), Ana Asenjo‐Bueno (Author), Patricia Plaza (Author), Natalia Carrillo‐López (Author), Gemma Olmos (Author), Susana López‐Ongil (Author), María Piedad Ruiz‐Torres (Author)
• Format: Book
• Published: Wiley, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hyperphosphatemia has been related to the development of sarcopenia in aging mice. We describe the intracellular mechanisms involved in the impairment of the myogenic differentiation promoted by hyperphosphatemia and analyse these mechanisms in the muscle from older mice. Methods...