Sirt1 Regulates Oxidative Stress in Oxygen-Glucose Deprived Hippocampal Neurons
Oxidative stress is an important mechanism of neonatal hypoxic-ischemic brain damage. Sirtuin1 (Sirt1) is a deacetylase that depends on NAD+, which has an important role in antioxidant metabolism. Furthermore, peroxisome proliferator-activated receptor γ-co-activator 1α (PGC-1α) is a key regulator o...
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Frontiers Media S.A.,
2020-08-01T00:00:00Z.
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