Frequency of CYP2D6 Alleles Including Structural Variants in the United States

• Main Authors: Andria L. Del Tredici (Author), Alka Malhotra (Author), Matthew Dedek (Author), Frank Espin (Author), Dan Roach (Author), Guang-dan Zhu (Author), Joseph Voland (Author), Tanya A. Moreno (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The CYP2D6 gene encodes an enzyme important in the metabolism of many commonly used medications. Variation in CYP2D6 is associated with inter-individual differences in medication response, and genetic testing is used to optimize medication therapy. This report describes a retrospective study of CYP2...