Better Control of Holder Pasteurization Results in Higher Retention of Human Milk Lactoferrin, IgA, and Lysozyme

Background: Holder pasteurization is commonly used in milk banks. We previously reported that the pattern of temperature and time may be different according to the pasteurizer used.Aim: The aim of our study was to assess the variances in pasteurization using two different devices: a standard pasteur...

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Main Authors: Rachel Buffin (Author), Stéphane Hays (Author), Jocelyne Drai (Author), Marie-Nathalie Sarda (Author), Jean-Charles Picaud (Author)
Format: Book
Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Rachel Buffin  |e author 
700 1 0 |a Rachel Buffin  |e author 
700 1 0 |a Stéphane Hays  |e author 
700 1 0 |a Jocelyne Drai  |e author 
700 1 0 |a Marie-Nathalie Sarda  |e author 
700 1 0 |a Jean-Charles Picaud  |e author 
700 1 0 |a Jean-Charles Picaud  |e author 
700 1 0 |a Jean-Charles Picaud  |e author 
245 0 0 |a Better Control of Holder Pasteurization Results in Higher Retention of Human Milk Lactoferrin, IgA, and Lysozyme 
260 |b Frontiers Media S.A.,   |c 2018-12-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2018.00381 
520 |a Background: Holder pasteurization is commonly used in milk banks. We previously reported that the pattern of temperature and time may be different according to the pasteurizer used.Aim: The aim of our study was to assess the variances in pasteurization using two different devices: a standard pasteurizer (Past STD) and an optimized pasteurizer (Past OPTI).Methods: Immunoglobulin A (IgA), lactoferrin (LF), and lysozyme (LZ) content were assessed before and after pasteurization of 24 donor human milk samples. The impact of the pasteurization device was evaluated by testing 50- to 200-mL samples.Results: Mean temperature and duration of the plateau were 1.5°C lower and 11 min shorter, respectively, with Past OPTI vs. Past STD. The loss of IgA, LF, and LZ was 17.6, 5.6, and 9.8% lower, respectively, with Past OPTI than with Past STD.Conclusions: Accurate control of temperature enabled better preservation of IgA, LF, and LZ in donor milk. Holder pasteurization should be optimized, and new techniques proposed to treat donor milk should be compared with Holder pasteurization performed with a well-controlled device under realistic conditions. 
546 |a EN 
690 |a human milk bank 
690 |a donor human milk 
690 |a quality control 
690 |a milk processing 
690 |a immunity 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 6 (2018) 
787 0 |n https://www.frontiersin.org/article/10.3389/fped.2018.00381/full 
787 0 |n https://doaj.org/toc/2296-2360 
856 4 1 |u https://doaj.org/article/f9fcb0f0a60c40bab9a2bbb4502c7615  |z Connect to this object online.