Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug-Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach

The anticonvulsant carbamazepine is frequently used in the long-term therapy of epilepsy and is a known substrate and inducer of cytochrome P450 (CYP) 3A4 and CYP2B6. Carbamazepine induces the metabolism of various drugs (including its own); on the other hand, its metabolism can be affected by vario...

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में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Laura Maria Fuhr (लेखक), Fatima Zahra Marok (लेखक), Nina Hanke (लेखक), Dominik Selzer (लेखक), Thorsten Lehr (लेखक)
स्वरूप: पुस्तक
प्रकाशित: MDPI AG, 2021-02-01T00:00:00Z.
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