Comparison Study of Two Differently Clicked 18F-Folates-Lipophilicity Plays a Key Role

• Main Authors: Kathrin Kettenbach (Author), Laura M. Reffert (Author), Hanno Schieferstein (Author), Stefanie Pektor (Author), Raphael Eckert (Author), Matthias Miederer (Author), Frank Rösch (Author), Tobias L. Ross (Author)
• Format: Book
• Published: MDPI AG, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Within the last decade, several folate-based radiopharmaceuticals for Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) have been evaluated; however, there is still a lack of suitable 18F-folates for clinical PET imaging. Herein, we report the synthesis and ev...