Design, synthesis, and biological evaluation of potent FAK-degrading PROTACs

FAK mediated tumour cell migration, invasion, survival, proliferation and regulation of tumour stem cells through its kinase-dependent enzymatic functions and kinase-independent scaffolding functions. At present, the development of FAK PROTACs has become one of the hotspots in current pharmaceutical...

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Main Authors: Qiaohua Qin (Author), Ruifeng Wang (Author), Qinglin Fu (Author), Guoqi Zhang (Author), Tianxiao Wu (Author), Nian Liu (Author), Ruicheng Lv (Author), Wenbo Yin (Author), Yin Sun (Author), Yixiang Sun (Author), Dongmei Zhao (Author), Maosheng Cheng (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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