DNA damage targeted therapy for advanced breast cancer

• Главные авторы: Vanessa Patel (Автор), Sandra Casimiro (Автор), Catarina Abreu (Автор), Tiago Barroso (Автор), Rita Teixeira de Sousa (Автор), Sofia Torres (Автор), Leonor Abreu Ribeiro (Автор), Gonçalo Nogueira-Costa (Автор), Helena Luna Pais (Автор), Conceição Pinto (Автор), Leila Costa (Автор), Luís Costa (Автор)
• Формат: ‌
• Опубликовано: Open Exploration Publishing Inc., 2024-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Breast cancer (BC) is the most prevalent malignancy affecting women worldwide, including Portugal. While the majority of BC cases are sporadic, hereditary forms account for 5-10% of cases. The most common inherited mutations associated with BC are germline mutations in the BReast CAncer (BRCA) 1/2 g...