DNA damage targeted therapy for advanced breast cancer

• Main Authors: Vanessa Patel (Author), Sandra Casimiro (Author), Catarina Abreu (Author), Tiago Barroso (Author), Rita Teixeira de Sousa (Author), Sofia Torres (Author), Leonor Abreu Ribeiro (Author), Gonçalo Nogueira-Costa (Author), Helena Luna Pais (Author), Conceição Pinto (Author), Leila Costa (Author), Luís Costa (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer (BC) is the most prevalent malignancy affecting women worldwide, including Portugal. While the majority of BC cases are sporadic, hereditary forms account for 5-10% of cases. The most common inherited mutations associated with BC are germline mutations in the BReast CAncer (BRCA) 1/2 g...