Unraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation

• Main Authors: Yaochen Xie (Author), Shuchen Gong (Author), Lingkun Wang (Author), Zhaoxu Yang (Author), Chen Yang (Author), Guilin Li (Author), Huiyan Zha (Author), Shuying Lv (Author), Boneng Xiao (Author), Xiaoyu Chen (Author), Zhenning Di (Author), Qiaojun He (Author), Jincheng Wang (Author), Qinjie Weng (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Huanglian Jiedu Decoction (HJD) is a well-known Traditional Chinese Medicine formula that has been used for liver protection in thousands of years. However, the therapeutic effects and mechanisms of HJD in treating drug-induced liver injury (DILI) remain unknown. In this study, a total of 2...