Impact of <i>N</i>-Acetyl Cysteine (NAC) on Tuberculosis (TB) Patients-A Systematic Review

• Main Authors: Daniel Adon Mapamba (Author), Elingarami Sauli (Author), Lucy Mrema (Author), Julieth Lalashowi (Author), David Magombola (Author), Joram Buza (Author), Willyhelmina Olomi (Author), Robert S. Wallis (Author), Nyanda Elias Ntinginya (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sustained TB infection overproduces reactive oxygen species (ROS) as a host defense mechanism. Research shows ROS is destructive to lung tissue. Glutathione (GSH) neutralizes ROS, although it is consumed. NAC is a precursor of GSH synthesis, and administering an appropriate dose of NAC to patients w...