A 9-aminoacridine derivative induces growth inhibition of Ehrlich ascites carcinoma cells and antinociceptive effect in mice

• Main Authors: Vivianne M. Mangueira (Author), Tatyanna K. G. de Sousa (Author), Tatianne M. Batista (Author), Renata A. de Abrantes (Author), Ana Paula G. Moura (Author), Rafael C. Ferreira (Author), Reinaldo N. de Almeida (Author), Renan M. Braga (Author), Fagner Carvalho Leite (Author), Karina C. de P. Medeiros (Author), Misael Azevedo T. Cavalcanti (Author), Ricardo O. Moura (Author), Geovana F. G. Silvestre (Author), Leônia M. Batista (Author), Marianna V. Sobral (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acridine derivatives have been found with anticancer and antinociceptive activities. Herein, we aimed to evaluate the toxicological, antitumor, and antinociceptive actions of N'-(6-chloro-2-methoxyacridin-9-yl)-2-cyanoacetohydrazide (ACS-AZ), a 9-aminoacridine derivative with antimalarial activ...