Spotlight on Human LL-37, an Immunomodulatory Peptide with Promising Cell-Penetrating Properties

• Main Authors: Marc Ferdinand Lensink (Author), Michel Vandenbranden (Author), Jean-Paul Dehaye (Author), Carole Nagant (Author), Michèle Seil (Author)
• Format: Book
• Published: MDPI AG, 2010-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cationic antimicrobial peptides are major components of innate immunity and help control the initial steps of the infectious process. They are expressed not only by immunocytes, but also by epithelial cells. They share an amphipathic secondary structure with a polar cationic site, which explains the...