A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells

A novel bis-lipoyl derivative containing 8-hydroxyquinoline scaffold (LA-HQ-LA, 5) was synthesized as a new multifunctional drug candidate with antioxidant, chelant, and neuroprotective properties for the treatment of neurodegenerative diseases. We have investigated the potential effectiveness of LA...

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Main Authors: Ivana Cacciatore (Author), Erika Fornasari (Author), Leonardo Baldassarre (Author), Catia Cornacchia (Author), Stefania Fulle (Author), Ester Sara Di Filippo (Author), Tiziana Pietrangelo (Author), Francesco Pinnen (Author)
Format: Book
Published: MDPI AG, 2013-01-01T00:00:00Z.
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