Protease-Activated Receptor Type 1 Activation Enhances Osteogenic Activity in Human Periodontal Ligament Stem Cells

• Main Authors: Emanuel Silva Rovai (Author), Lucas Macedo Batitucci Ambrósio (Author), Bruno Nunes de França (Author), Letícia Rodrigues de Oliveira (Author), Letícia Miquelitto Gasparoni (Author), Carla Renata Sipert (Author), Marinella Holzhausen (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protease-activated receptor 1 (PAR1) has been associated to tissue repair and bone healing. The aim of the present study was to evaluate the effect of PAR1 activation on the osteogenic activity of human periodontal ligament stem cells (PDLSCs). PDLSCs were cultured in the presence of PAR1-selective...