NQO1 Deficiency Aggravates Renal Injury by Dysregulating Vps34/ATG14L Complex during Autophagy Initiation in Diabetic Nephropathy

• Asıl Yazarlar: Geum-Lan Hong (Yazar), Kyung-Hyun Kim (Yazar), Chul-Ho Lee (Yazar), Tae-Won Kim (Yazar), Ju-Young Jung (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Diabetic nephropathy (DN) is one of the causes of end-stage renal failure, featuring renal fibrosis. However, autophagy, a vital process for intracellular homeostasis, can counteract renal fibrosis. Moreover, NAD(P)H: quinone dehydrogenase 1 (NQO1) modulates the ratios of reduced/oxidized nicotinami...