Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function

The p21-activated kinase 1 (PAK1) is required for insulin-stimulated glucose uptake in skeletal muscle cells. However, whether PAK1 regulates skeletal muscle mitochondrial function, which is a central determinant of insulin sensitivity, is unknown. Here, the effect of modulating PAK1 levels (knockdo...

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Main Authors: Rekha Balakrishnan (Author), Pablo A. Garcia (Author), Rajakrishnan Veluthakal (Author), Janice M. Huss (Author), Joseph M. Hoolachan (Author), Debbie C. Thurmond (Author)
Format: Book
Published: MDPI AG, 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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