Inhibitory mechanism of peptides with a repeating hydrophobic and hydrophilic residue pattern on interleukin-10

• Main Authors: Guoying Ni (Author), Yuejian Wang (Author), Scott Cummins (Author), Shelley Walton (Author), Kate Mounsey (Author), Xiaosong Liu (Author), Ming Q. Wei (Author), Tianfang Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin 10 (IL-10) is a cytokine that is able to downregulate inflammation. Its overexpression is directly associated with the difficulty in the clearance of chronic viral infections, such as chronic hepatitis B, hepatitis C and HIV infection, and infection-related cancer. IL-10 signaling blocka...