Use of factorial design in formulation and evaluation of intrarectal in situ gel of sumatriptan
The study's goal was to create an in situ intrarectal mucoadhesive gel of sumatriptan (SMT) combining mucoadhesive polymer (xyloglucan) and thermosensitive polymers (poloxamer 407 and poloxamer 188) to prolong rectal residence time for treatment of migraines. Nine SMT mucoadhesive rectal in sit...
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Wolters Kluwer Medknow Publications,
2023-01-01T00:00:00Z.
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