A novel biomarker of fibrofatty replacement in dystrophinopathies identified by integrating transcriptome, magnetic resonance imaging, and pathology data

• Main Authors: Zhihao Xie (Author), Chang Liu (Author), Chengyue Sun (Author), Yanyu Lu (Author), Shiyi Wu (Author), Yilin Liu (Author), Qi Wang (Author), Yalan Wan (Author), Yikang Wang (Author), Meng Yu (Author), Lingchao Meng (Author), Jianwen Deng (Author), Wei Zhang (Author), Zhaoxia Wang (Author), Chunxia Yang (Author), Yun Yuan (Author), Zhiying Xie (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We aimed to analyse genome‐wide transcriptome differences between Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) patients and identify biomarkers that correlate well with muscle magnetic resonance imaging (MRI) and histological fibrofatty replacement in bot...