PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer

• Main Authors: Zhenliang Sun (Author), Yang Zhang (Author), Duo Cao (Author), Xufeng Wang (Author), Xuebing Yan (Author), Hao Li (Author), Linsheng Huang (Author), Xiao Qu (Author), Cheng Kong (Author), Huanglong Qin (Author), Man Wang (Author), Wei Xu (Author), Lin Liang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although the cancer immunotherapy represents one of the most promising strategies for cancer treatment, the PD-1/PD-L1 pathway, which involves a receptor-ligand interaction, can induced immunosuppression by disabling tumor-infiltrating lymphocytes (TILs). In the present study, we coupled a PD-L1 (Pr...