siRNA-induced silencing of hypoxia-inducible factor 3α (HIF3α) increases endurance capacity in rats

• Main Authors: S Drozdovska (Author), B Gavenauskas (Author), T Drevytska (Author), V Nosar (Author), V Nagibin (Author), I Mankovska (Author), V Dosenko (Author)
• Format: Book
• Published: Termedia Publishing House, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Molecular mechanisms of adaptation to exercise despite a large number of studies remain unclear. One of the crucial factors in this process is hypoxia inducible factor (HIF) that regulates transcription of many target genes encoding proteins that are implicated in molecular adaptation to hypoxia. Ex...