The expression of Bcl-2 in oral squamous cell carcinoma-A review

Currently, oral cancer is one of the most alarming health problems facing mankind. More than 90% of all oral cancers are oral squamous cell carcinoma (OSCC). BCL-2 proteins are one of the most prominent anti-apoptotic proteins expressed in OSCC. They contribute to cancer development and mediate resi...

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Bibliographic Details
Main Authors: Jayakumar Arumugam (Author), Nadeem Jeddy (Author), Ananthalakshmi Ramamurthy (Author), Radhika Thangavelu (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Jayakumar Arumugam  |e author 
700 1 0 |a Nadeem Jeddy  |e author 
700 1 0 |a Ananthalakshmi Ramamurthy  |e author 
700 1 0 |a Radhika Thangavelu  |e author 
245 0 0 |a The expression of Bcl-2 in oral squamous cell carcinoma-A review 
260 |b Wolters Kluwer Medknow Publications,   |c 2017-01-01T00:00:00Z. 
500 |a 0975-8844 
500 |a 10.4103/jofs.jofs_88_16 
520 |a Currently, oral cancer is one of the most alarming health problems facing mankind. More than 90% of all oral cancers are oral squamous cell carcinoma (OSCC). BCL-2 proteins are one of the most prominent anti-apoptotic proteins expressed in OSCC. They contribute to cancer development and mediate resistance to current anticancer treatments. Various studies have been conducted to evaluate the expression of Bcl-2 in OSCC. This article emphasizes the importance of Bcl-2 expression as a prognostic indicator in OSCC. 
546 |a EN 
690 |a apoptosis 
690 |a Bcl-2 
690 |a carcinogenesis 
690 |a OSCC 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Journal of Orofacial Sciences, Vol 9, Iss 2, Pp 71-74 (2017) 
787 0 |n http://www.jofs.in/article.asp?issn=0975-8844;year=2017;volume=9;issue=2;spage=71;epage=74;aulast=Arumugam 
787 0 |n https://doaj.org/toc/0975-8844 
856 4 1 |u https://doaj.org/article/fa73f398d71f45f8942a7054c5ccbc8f  |z Connect to this object online.