Cucurbitacin B regulates lung cancer cell proliferation and apoptosis via inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis

• Autori principali: Jian-Hua Liu (Autore), Chen Li (Autore), Liang Cao (Autore), Chang-Hong Zhang (Autore), Zhi-Hua Zhang (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Context Lung cancer, the most common type of cancer, has a high mortality rate. Cucurbitacin B (CuB), a natural compound extracted from Cucurbitaceae plants, has antitumor effects. Objective We investigated the role of CuB on lung cancer and its potential mechanisms. Materials and methods A549 cells...