Topotecan and Ginkgolic Acid Inhibit the Expression and Transport Activity of Human Organic Anion Transporter 3 by Suppressing SUMOylation of the Transporter

Organic anion transporter 3 (OAT3), expressed at the basolateral membrane of kidney proximal tubule cells, facilitates the elimination of numerous metabolites, environmental toxins, and clinically important drugs. An earlier investigation from our laboratory revealed that OAT3 expression and transpo...

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Main Authors: Zhou Yu (Author), Guofeng You (Author)
Format: Book
Published: MDPI AG, 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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