Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen.

• Main Authors: Farnaz Zahedifard (Author), Elham Gholami (Author), Tahereh Taheri (Author), Yasaman Taslimi (Author), Fatemeh Doustdari (Author), Negar Seyed (Author), Fatemeh Torkashvand (Author), Claudio Meneses (Author), Barbara Papadopoulou (Author), Shaden Kamhawi (Author), Jesus G Valenzuela (Author), Sima Rafati (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Novel vaccination approaches are needed to prevent leishmaniasis. Live attenuated vaccines are the gold standard for protection against intracellular pathogens such as Leishmania and there have been new developments in this field. The nonpathogenic to humans lizard protozoan parasite, Leishmania (L)...