SYNTHESIS, COMPUTER AIDED SCREENING AND PHARMACOLOGICAL EVALUATION OF 2/3-SUBSTITUTED-6(4-METHYLPHENYL)-4,5-DIHYDROPYRIDAZIN3(2H)-ONES, AND PYRIDAZINE SUBSTITUTED TRIAZINE

• Main Authors: Asif Husain (Author), Sukhbir Lal Khokra (Author), Sonakshi Seth (Author), Shama S Garg (Author), Pawan Kaushik (Author), Aftab Ahmad (Author), Shah Alam Khan (Author)
• Format: Book
• Published: Universitas Gadjah Mada, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present research work involved synthesis of some novel pyridazine derivatives and evaluation of their analgesic and anti-inflammatory activities in experimental animals to obtain safer non-steroidal anti-inflammatory drugs (NSAIDs). Friedal craft acylation reaction of succinic anhydride with tol...