Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro

• Ngā kaituhi matua: Yun-Yi Ma (Author), Huei-Wen Chen (Author), Chii-Ruey Tzeng (Author)
• Hōputu: Pukapuka
• I whakaputaina: BMC, 2017-07-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Abstract Background In human IVF, embryos cultured with a lower O2 tension (5%) can give rise to higher success rates when compared with normoxic conditions (20%). However, the mechanisms behind the beneficial effects of reduced oxygen tension in embryogenesis remain unclear. The aim of this study w...