Next Generation Sequencing in Newborn Screening in the United Kingdom National Health Service

• Main Authors: Julia C. van Campen (Author), Elizabeth S. A. Sollars (Author), Rebecca C. Thomas (Author), Clare M. Bartlett (Author), Antonio Milano (Author), Matthew D. Parker (Author), Jennifer Dawe (Author), Peter R. Winship (Author), Gerrard Peck (Author), Darren Grafham (Author), Richard J. Kirk (Author), James R. Bonham (Author), Anne C. Goodeve (Author), Ann Dalton (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Next generation DNA sequencing (NGS) has the potential to improve the diagnostic and prognostic utility of newborn screening programmes. This study assesses the feasibility of automating NGS on dried blood spot (DBS) DNA in a United Kingdom National Health Service (UK NHS) laboratory. An NGS panel t...