Discovery and antitumor evaluation of novel inhibitors of spermine oxidase

• Main Authors: Lidan Sun (Author), Jianlin Yang (Author), Yu Qin (Author), Yanlin Wang (Author), Hongyan Wu (Author), You Zhou (Author), Chunyu Cao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing knowledge of the relationship between cancer and dysregulated polyamine catabolism suggests interfering with aberrant polyamine metabolism for anticancer therapy that will have considerable clinical promise. SMO (spermine oxidase) plays an essential role in regulating the polyamines homeo...