Tiamulin-Resistant Mutants of the Thermophilic Bacterium <i>Thermus thermophilus</i>
Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant mutants of the thermophilic b...
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MDPI AG,
2020-06-01T00:00:00Z.
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