Novel Efficient Lipid-Based Delivery Systems Enable a Delayed Uptake and Sustained Expression of mRNA in Human Cells and Mouse Tissues

• Main Authors: Artem G. Fedorovskiy (Author), Denis N. Antropov (Author), Anton S. Dome (Author), Pavel A. Puchkov (Author), Daria M. Makarova (Author), Maria V. Konopleva (Author), Anastasiya M. Matveeva (Author), Eugenia A. Panova (Author), Elena V. Shmendel (Author), Mikhail A. Maslov (Author), Sergey E. Dmitriev (Author), Grigory A. Stepanov (Author), Oleg V. Markov (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over the past decade, mRNA-based therapy has displayed significant promise in a wide range of clinical applications. The most striking example of the leap in the development of mRNA technologies was the mass vaccination against COVID-19 during the pandemic. The emergence of large-scale technology an...