Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury

• Main Authors: Han Xu (Author), Sicong Xu (Author), Liyan Li (Author), Yuhuang Wu (Author), Shiying Mai (Author), Yiqiang Xie (Author), Yinfeng Tan (Author), Ailing Li (Author), Fengming Xue (Author), Xiaoning He (Author), Yonghui Li (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Acute lung injury (ALI) is a severe inflammatory disease, underscoring the urgent need for novel treatments. Nauclea officinalis Pierre ex Pitard (Danmu in Chinese, DM) is effective in treating inflammatory respiratory diseases. However, there is still no evidence of its protecti...