Identification of Blood Transport Proteins to Carry Temoporfin: A Domino Approach from Virtual Screening to Synthesis and In Vitro PDT Testing

Identification of Blood Transport Proteins to Carry Temoporfin: A Domino Approach from Virtual Screening to Synthesis and In Vitro PDT Testing

Temoporfin (mTHPC) is one of the most promising photosensitizers used in photodynamic therapy (PDT). Despite its clinical use, the lipophilic character of mTHPC still hampers the full exploitation of its potential. Low solubility in water, high tendency to aggregate, and low biocompatibility are the...

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Main Authors: Alessia Marconi (Author), Giulia Giugliano (Author), Matteo Di Giosia (Author), Tainah Dorina Marforio (Author), Michele Trivini (Author), Eleonora Turrini (Author), Carmela Fimognari (Author), Francesco Zerbetto (Author), Edoardo Jun Mattioli (Author), Matteo Calvaresi (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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