Formulation and evaluation of 5-fluorouracil controlled release chronotherapeutic drug delivery system (CTDDS) for colorectal cancer

• Main Authors: Hammad Ayaz (Author), Muhammad Ahmad (Author), Mustafa Kazmi (Author), Husnain Ahmed (Author), Talib Hussain (Author), Ishtiaq Jeelani (Author)
• Format: Book
• Published: AMMANIF, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: As most of the drugs disintegrate and dissolve in stomach before reaching the target site and to substitute intravenous (IV) route based chrono modulated chemotherapy, oral colon target drug delivery system was formed. The aim of this study was to design, develop, and evaluate a colon tar...