Positive allosteric modulation of mGluR5 accelerates extinction learning but not relearning following methamphetamine self-administration

• Главные авторы: Peter R Kufahl (Автор), Lauren E Hood (Автор), Natali E Nemirovsky (Автор), Piroska eBarabas (Автор), Casey eHalstengard (Автор), Angel eVilla (Автор), Elisabeth eMoore (Автор), Lucas R Watterson (Автор), M Foster eOlive (Автор)
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• Опубликовано: Frontiers Media S.A., 2012-11-01T00:00:00Z.
• Предметы: article
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Recent studies have implicated glutamate neurotransmission as an important substrate for the extinction of conditioned behaviors, including responding for drug reinforcement. Positive allosteric modulation of the type-5 metabotropic glutamate receptor (mGluR5) in particular has emerged as a treatmen...