BAY 11-7082 Is a Broad-Spectrum Inhibitor with Anti-Inflammatory Activity against Multiple Targets

• المؤلفون الرئيسيون: Jaehwi Lee (مؤلف), Man Hee Rhee (مؤلف), Eunji Kim (مؤلف), Jae Youl Cho (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2012-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BAY 11-7082 (BAY) is an inhibitor of κB kinase (IKK) that has pharmacological activities that include anticancer, neuroprotective, and anti-inflammatory effects. In this study, BAY-pharmacological target pathways were further characterized to determine how this compound simultaneously suppresses var...