Effects of the EM CYP2C19 type and MDR1 3435CC gene on Helicobacter pylori eradication rate in patients with duodenal ulcer by the four-drug regimen of rabeprazole, bismuth, tetracycline, and tinidazole

• Main Authors: Liem T. Nguyen (Author), Vuong B. Nguyen (Author), Tu V. Tran (Author), Loan T. T. Le (Author), Mai H. T. Phuong (Author), Thang Nguyen (Author)
• Format: Book
• Published: Pensoft Publishers, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The MDR1 genotype and the CYP2C19 phenotype determine how much PPI is absorbed from the gut and how much is processed in the liver. Objective: To assess the impact of CYP2C19 and MDR1 C3435T gene polymorphisms on the efficiency of H. pylori eradication treatment with a 4-drug regimen of...