Synthesis and antiviral activity of a series of novel N-phenylbenzamide and N-phenylacetophenone compounds as anti-HCV and anti-EV71 agents

A series of novel N-phenylbenzamide and N-phenylacetophenone compounds were synthesized and evaluated for their antiviral activity against HCV and EV71 (strain SZ-98). The biological results showed that three compounds (23, 25 and 41) exhibited considerable anti-HCV activity (IC50=0.57-7.12 μmol/L)...

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Main Authors: Zhi Jiang (Author), Huiqiang Wang (Author), Yanping Li (Author), Zonggen Peng (Author), Yuhuan Li (Author), Zhuorong Li (Author)
Format: Book
Published: Elsevier, 2015-05-01T00:00:00Z.
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