Doxepin Exacerbates Renal Damage, Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Urinary Chromium Loss in Obese Mice

• Main Authors: Geng-Ruei Chang (Author), Po-Hsun Hou (Author), Wei-Cheng Yang (Author), Chao-Min Wang (Author), Pei-Shan Fan (Author), Huei-Jyuan Liao (Author), To-Pang Chen (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxepin is commonly prescribed for depression and anxiety treatment. Doxepin-related disruptions to metabolism and renal/hepatic adverse effects remain unclear; thus, the underlying mechanism of action warrants further research. Here, we investigated how doxepin affects lipid change, glucose homeost...