Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis

• Main Authors: Daoyuan Lv (Author), Song Jiang (Author), Mingchao Zhang (Author), Xiaodong Zhu (Author), Fan Yang (Author), Hui Wang (Author), Shen Li (Author), Feng Liu (Author), Caihong Zeng (Author), Weisong Qin (Author), Limin Li (Author), Zhihong Liu (Author)
• Format: Book
• Published: Karger Publishers, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Membranous nephropathy (MN) is a common chronic kidney disease in adults and a major challenge of clinical practice for its treatment. Despite major advances, since the discovery of the phospholipase A2 receptor as the major autoantigen of podocytes in MN, the mechanisms leading to glo...